p73 activates transcriptional signatures of basal lineage identity and ciliogenesis in pancreatic ductal adenocarcinoma

During the progression of pancreatic ductal adenocarcinoma (PDAC), tumor cells are known to acquire transcriptional and morphological properties of the basal (also known as squamous) epithelial lineage, which leads to more aggressive disease characteristics. Here, we show that a subset of basal-like...

Descripción completa

Detalles Bibliográficos
Autores principales: Hur, Stella K., Somerville, Tim D.D., Wu, Xiaoli S., Maia-Silva, Diogo, Demerdash, Osama E., Tuveson, David A., Notta, Faiyaz, Vakoc, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153254/
https://www.ncbi.nlm.nih.gov/pubmed/37131797
http://dx.doi.org/10.1101/2023.04.20.537667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153254/
https://www.ncbi.nlm.nih.gov/pubmed/37131797
http://dx.doi.org/10.1101/2023.04.20.537667

Ejemplares similares