Cargando…
Pharmacological Induction of mesenchymal-epithelial transition chemosensitizes breast cancer cells and prevents metastatic progression
The epithelial-mesenchymal transition (EMT) is a developmental program co-opted by tumor cells that aids the initiation of the metastatic cascade. Tumor cells that undergo EMT are relatively chemoresistant, and there are currently no therapeutic avenues specifically targeting cells that have acquire...
Autores principales: | Bagheri, Meisam, Aisha Mohamed, Gadisti, Mohamed Saleem, Mohammed Ashick, Ognjenovic, Nevena B., Lu, Hanxu, Kolling, Fred W., Wilkins, Owen M., Das, Subhadeep, La Croix, Ian S., Nagaraj, Shivashankar H., Muller, Kristen E., Gerber, Scott A., Miller, Todd W., Pattabiraman, Diwakar R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153261/ https://www.ncbi.nlm.nih.gov/pubmed/37131809 http://dx.doi.org/10.1101/2023.04.19.537586 |
Ejemplares similares
-
Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits
por: Mohamed, Gadisti Aisha, et al.
Publicado: (2023) -
Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer
por: Brown, Meredith S., et al.
Publicado: (2022) -
Alteration of DNMT1/DNMT3A by eribulin elicits global DNA methylation changes with potential therapeutic implications for triple-negative breast cancer
por: Bagheri, Meisam, et al.
Publicado: (2023) -
Distinct cytosine modification profiles define epithelial-to-mesenchymal cell-state transitions
por: Lee, Min Kyung, et al.
Publicado: (2022) -
Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis
por: Malysheva, Valeriya, et al.
Publicado: (2016)