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Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIP

It is well-established that activation of heterotrimeric G-proteins (Gαβγ) by G-protein-coupled receptors (GPCRs) stimulated by neurotransmitters is a key mechanism underlying neuromodulation. Much less is known about how G-protein regulation after receptor-mediated activation contributes to neuromo...

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Detalles Bibliográficos
Autores principales: Luebbers, Alex, Zhou, Myles, Eyles, Stephen J, Garcia-Marcos, Mikel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153262/
https://www.ncbi.nlm.nih.gov/pubmed/37131787
http://dx.doi.org/10.1101/2023.04.20.537566