Intra-Articular Delivery of an Indoleamine 2,3-Dioxygenase Galectin-3 Fusion Protein for Osteoarthritis Treatment in Male Lewis Rats

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OBJECTIVE: Controlling joint inflammation can improve osteoarthritis (OA) symptoms; however, current treatments often fail to provide long-term effects. We have developed an indoleamine 2,3-dioxygenase and galectin-3 fusion protein (IDO-Gal3). IDO converts tryptophan to kynurenines, directing the lo...

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Detalles Bibliográficos
Autores principales: Partain, Brittany D., Bracho-Sanchez, Evelyn, Farhadi, Shaheen A., Yarmola, Elena G., Keselowsky, Benjamin G., Hudalla, Gregory A., Allen, Kyle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153358/
https://www.ncbi.nlm.nih.gov/pubmed/37131836
http://dx.doi.org/10.21203/rs.3.rs-2753443/v1

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