E-WE thrombin, a protein C activator, reduces disease severity and spinal cord inflammation in relapsing-remitting murine experimental autoimmune encephalomyelitis

OBJECTIVE: Relapses in patients with relapsing-remitting multiple sclerosis (RRMS) are typically treated with high-dose corticosteroids including methylprednisolone. However, high-dose corticosteroids are associated with significant adverse effects, can increase the risk for other morbidities, and o...

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Detalles Bibliográficos
Autores principales: Verbout, Norah G, Su, Weiping, Pham, Peter, Jordan, Kelley, Kohs, Tia CL, Tucker, Erik I, McCarty, Owen JT, Sherman, Larry S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153372/
https://www.ncbi.nlm.nih.gov/pubmed/37131631
http://dx.doi.org/10.21203/rs.3.rs-2802415/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153372/
https://www.ncbi.nlm.nih.gov/pubmed/37131631
http://dx.doi.org/10.21203/rs.3.rs-2802415/v1

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