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E-WE thrombin, a protein C activator, reduces disease severity and spinal cord inflammation in relapsing-remitting murine experimental autoimmune encephalomyelitis
OBJECTIVE: Relapses in patients with relapsing-remitting multiple sclerosis (RRMS) are typically treated with high-dose corticosteroids including methylprednisolone. However, high-dose corticosteroids are associated with significant adverse effects, can increase the risk for other morbidities, and o...
Autores principales: | Verbout, Norah G, Su, Weiping, Pham, Peter, Jordan, Kelley, Kohs, Tia CL, Tucker, Erik I, McCarty, Owen JT, Sherman, Larry S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153372/ https://www.ncbi.nlm.nih.gov/pubmed/37131631 http://dx.doi.org/10.21203/rs.3.rs-2802415/v1 |
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