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A bioengineered immunocompetent human leukemia chip for preclinical screening of CAR T cell immunotherapy

Chimeric antigen receptor (CAR) T cell immunotherapy is promising for treatment of blood cancers; however, clinical benefits remain unpredictable, necessitating development of optimal CAR T cell products. Unfortunately, current preclinical evaluation platforms are inadequate due to their limited phy...

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Detalles Bibliográficos
Autores principales:	Ma, Chao, Wang, Huishu, Liu, Lunan, Tong, Jie, Witkowski, Matthew T., Aifantis, Iannis, Ghassemi, Saba, Chen, Weiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153390/ https://www.ncbi.nlm.nih.gov/pubmed/37131801 http://dx.doi.org/10.21203/rs.3.rs-2762929/v1

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