Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma

MYC's key role in oncogenesis and tumor progression has long been established for most human cancers. In melanoma, its deregulated activity by amplification of 8q24 chromosome or by upstream signaling coming from activating mutations in the RAS/RAF/MAPK pathway—the most predominantly mutated pa...

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Detalles Bibliográficos
Autores principales: Zacarías-Fluck, Mariano F., Massó-Vallés, Daniel, Giuntini, Fabio, González-Larreategui, Íñigo, Kaur, Jastrinjan, Casacuberta-Serra, Sílvia, Jauset, Toni, Martínez-Martín, Sandra, Martín-Fernández, Génesis, Serrano del Pozo, Erika, Foradada, Laia, Grueso, Judit, Nonell, Lara, Beaulieu, Marie-Eve, Whitfield, Jonathan R., Soucek, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153459/
https://www.ncbi.nlm.nih.gov/pubmed/37024284
http://dx.doi.org/10.1101/gad.350078.122

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