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Cis interactions in the Irf8 locus regulate stage-dependent enhancer activation

Individual elements within a superenhancer can act in a cooperative or temporal manner, but the underlying mechanisms remain obscure. We recently identified an Irf8 superenhancer, within which different elements act at distinct stages of type 1 classical dendritic cell (cDC1) development. The +41-kb...

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Detalles Bibliográficos
Autores principales:	Liu, Tian-Tian, Ou, Feiya, Belk, Julia A., Bagadia, Prachi, Anderson, David A., Durai, Vivek, Yao, Winnie, Satpathy, Ansuman T., Murphy, Theresa L., Murphy, Kenneth M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2023
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153461/ https://www.ncbi.nlm.nih.gov/pubmed/36990511 http://dx.doi.org/10.1101/gad.350339.122

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