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Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction

Oncogene-induced senescence is a phenomenon in which aberrant oncogene expression causes non-transformed cells to enter a non-proliferative state. Cells undergoing oncogenic induction display phenotypic heterogeneity, with some cells senescing and others remaining proliferative. The causes of hetero...

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Detalles Bibliográficos
Autores principales: Chen, Jia-Yun, Hug, Clemens, Reyes, José, Tian, Chengzhe, Gerosa, Luca, Fröhlich, Fabian, Ponsioen, Bas, Snippert, Hugo J.G., Spencer, Sabrina L., Jambhekar, Ashwini, Sorger, Peter K., Lahav, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153468/
https://www.ncbi.nlm.nih.gov/pubmed/36920903
http://dx.doi.org/10.1016/j.celrep.2023.112252