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Effects of nandrolone decanoate on telomere length and clinical outcome in patients with telomeropathies: a prospective trial

Androgens have been reported to elongate telomeres in retrospective and prospective trials with patients with telomeropathies, mainly with bone marrow failure. In our single-arm prospective clinical trial (clinicaltrials gov. Identifier: NCT02055456), 17 patients with short telomeres and/or germline...

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Detalles Bibliográficos
Autores principales: Clé, Diego V., Catto, Luiz Fernando B., Gutierrez-Rodrigues, Fernanda, Donaires, Flávia S., Pinto, Andre L., Santana, Barbara A., Darrigo Jr., Luiz Guilherme, Valera, Elvis T., KoenigkamSantos, Marcel, Baddini-Martinez, José, Young, Neal S., Martinez, Edson Z., Calado, Rodrigo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153533/
https://www.ncbi.nlm.nih.gov/pubmed/36579443
http://dx.doi.org/10.3324/haematol.2022.281808