The effects of benralizumab on airway geometry and dynamics in severe eosinophilic asthma: a single-arm study design exploring a functional respiratory imaging approach

BACKGROUND: Severe eosinophilic asthma (SEA) is characterised by elevated blood/sputum eosinophil counts and airway inflammation, which can lead to mucus plug-mediated airway obstruction, increased exacerbation frequency, declines in lung function, and death. Benralizumab targets the alpha-subunit o...

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Detalles Bibliográficos
Autores principales: Genofre, Eduardo, Carstens, Donna, DeBacker, Wilfried, Muchmore, Patrick, Panettieri, Reynold A., Rhodes, Kirsty, Shih, Vivian H., Trudo, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154186/
https://www.ncbi.nlm.nih.gov/pubmed/37131265
http://dx.doi.org/10.1186/s12931-023-02415-4

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