Systemic GDF11 attenuates depression-like phenotype in aged mice via stimulation of neuronal autophagy

Cognitive decline and mood disorders increase in frequency with age. Many efforts are focused on the identification of molecules and pathways to treat these conditions. Here, we demonstrate that systemic administration of growth differentiation factor 11 (GDF11) in aged mice improves memory and alle...

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Detalles Bibliográficos
Autores principales: Moigneu, Carine, Abdellaoui, Soumia, Ramos-Brossier, Mariana, Pfaffenseller, Bianca, Wollenhaupt-Aguiar, Bianca, de Azevedo Cardoso, Taiane, Camus, Claire, Chiche, Aurélie, Kuperwasser, Nicolas, Azevedo da Silva, Ricardo, Pedrotti Moreira, Fernanda, Li, Han, Oury, Franck, Kapczinski, Flávio, Lledo, Pierre-Marie, Katsimpardi, Lida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154197/
https://www.ncbi.nlm.nih.gov/pubmed/37118117
http://dx.doi.org/10.1038/s43587-022-00352-3

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