Intracrine activity involving NAD-dependent circadian steroidogenic activity governs age-associated meibomian gland dysfunction

Canonically, hormones are produced in the endocrine organs and delivered to target tissues. However, for steroids, the concept of tissue intracrinology, whereby hormones are produced in the tissues where they exert their effect without release into circulation, has been proposed, but its role in phy...

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Detalles Bibliográficos
Autores principales: Sasaki, Lena, Hamada, Yuki, Yarimizu, Daisuke, Suzuki, Tomo, Nakamura, Hiroki, Shimada, Aya, Pham, Khanh Tien Nguyen, Shao, Xinyan, Yamamura, Koki, Inatomi, Tsutomu, Morinaga, Hironobu, Nishimura, Emi K., Kudo, Fujimi, Manabe, Ichiro, Haraguchi, Shogo, Sugiura, Yuki, Suematsu, Makoto, Kinoshita, Shigeru, Machida, Mamiko, Nakajima, Takeshi, Kiyonari, Hiroshi, Okamura, Hitoshi, Yamaguchi, Yoshiaki, Miyake, Takahito, Doi, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154200/
https://www.ncbi.nlm.nih.gov/pubmed/37117756
http://dx.doi.org/10.1038/s43587-021-00167-8

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