Cargando…

Serine/threonine kinase TBK1 promotes cholangiocarcinoma progression via direct regulation of β-catenin

Cholangiocarcinoma (CCA) is a highly heterogeneous and metastatic malignancy with a poor prognosis even after curative hepatectomy. Studies exploring its pathogenesis and identifying effective therapeutic targets are urgently needed. In this study, we found that TANK-binding kinase 1 (TBK1), a serin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Chong-Qing, Chu, Zhen-Zhen, Zhang, Di, Xiao, Yang, Zhou, Xing-Yan, Wu, Jun-Ru, Yuan, Hui, Jiang, Yu-Chuan, Chen, Dong, Zhang, Ji-Chun, Yao, Nan, Chen, Kai-Yun, Hong, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154201/ https://www.ncbi.nlm.nih.gov/pubmed/36928362 http://dx.doi.org/10.1038/s41388-023-02651-4

Ejemplares similares

Identification of highly specific antibodies for Serine/threonine-protein kinase TBK1 for use in immunoblot, immunoprecipitation and immunofluorescence
por: Alshafie, Walaa, et al.
Publicado: (2022)

Serine/Threonine Protein Kinase STK16
por: Wang, Junjun, et al.
Publicado: (2019)

Rhabdovirus Infection Is Dependent on Serine/Threonine Kinase AP2-Associated Kinase 1
por: Luo, Jun, et al.
Publicado: (2020)

Serine threonine tyrosine kinase 1 is a potential prognostic marker in colorectal cancer
por: Hu, Liang, et al.
Publicado: (2015)

Screening for serine/threonine kinases phosphorylating Stat5
por: Berger, Angelika, et al.
Publicado: (2011)

The serine threonine kinase RIP3: lost and found
por: Morgan, Michael J., et al.
Publicado: (2015)

Serine/Threonine‐Protein Kinase 3 Facilitates Myocardial Repair After Cardiac Injury Possibly Through the Glycogen Synthase Kinase‐3β/β‐Catenin Pathway
por: Li, Ya‐Fei, et al.
Publicado: (2021)

Overexpression of Citron Rho-Interacting Serine/Threonine Kinase Associated with Poor Outcome in Bladder Cancer
por: Shou, Jiafeng, et al.
Publicado: (2020)

Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity
por: Chen, Catherine, et al.
Publicado: (2014)

The Serine/Threonine Kinase AP2-Associated Kinase 1 Plays an Important Role in Rabies Virus Entry
por: Wang, Chong, et al.
Publicado: (2019)

Genome-wide survey of putative Serine/Threonine protein kinases in cyanobacteria
por: Zhang, Xiaowen, et al.
Publicado: (2007)

A Novel Family of Serine/Threonine Kinases Participating in Spermiogenesis
por: Kueng, Peter, et al.
Publicado: (1997)

Lacticin 481 Synthetase as a General Serine/Threonine Kinase
por: You, Young Ok, et al.
Publicado: (2009)

Structural insights into the polypharmacological activity of quercetin on serine/threonine kinases
por: Baby, Bincy, et al.
Publicado: (2016)

ATM Serine/Threonine Kinase and its Role in Pancreatic Risk
por: Nanda, Neha, et al.
Publicado: (2020)

Microtubule-Associated Serine/Threonine (MAST) Kinases in Development and Disease
por: Rumpf, Marie, et al.
Publicado: (2023)

Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration
por: Matsuki, Tohru, et al.
Publicado: (2013)

MicroRNA-299-5p inhibits cell metastasis in breast cancer by directly targeting serine/threonine kinase 39
por: Li, Chenxing, et al.
Publicado: (2020)

Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
por: Rakette, Sonja, et al.
Publicado: (2012)

Correlated Mutation Analysis on the Catalytic Domains of Serine/Threonine Protein Kinases
por: Xu, Feng, et al.
Publicado: (2009)

Impact of Serine/Threonine Protein Kinases on the Regulation of Sporulation in Bacillus subtilis
por: Pompeo, Frédérique, et al.
Publicado: (2016)

Evolutionary divergence in the conformational landscapes of tyrosine vs serine/threonine kinases
por: Gizzio, Joan, et al.
Publicado: (2022)

Evaluation of functionality for serine and threonine phosphorylation with different evolutionary ages in human and mouse
por: Miao, Benpeng, et al.
Publicado: (2018)

Role of serine/threonine kinase 33 methylation in colorectal cancer and its clinical significance
por: Yin, Ming-Di, et al.
Publicado: (2018)

Identification of novel natural inhibitors targeting AKT Serine/Threonine Kinase 1 (AKT1) by computational study
por: Zhong, Sheng, et al.
Publicado: (2022)

SGK1, a Serine/Threonine Kinase, Inhibits Prototype Foamy Virus Replication
por: Zhang, Junshi, et al.
Publicado: (2022)

Selenoproteins Protect Against Avian Liver Necrosis by Metabolizing Peroxides and Regulating Receptor Interacting Serine Threonine Kinase 1/Receptor Interacting Serine Threonine Kinase 3/Mixed Lineage Kinase Domain-Like and Mitogen-Activated Protein Kinase Signaling
por: Li, Tong, et al.
Publicado: (2021)

The Eukaryotic-Type Serine/Threonine Protein Kinase Stk Is Required for Biofilm Formation and Virulence in Staphylococcus epidermidis
por: Liu, Qian, et al.
Publicado: (2011)

Correction: Correlated Mutation Analysis on the Catalytic Domains of Serine/Threonine Protein Kinases
por: Xu, Feng, et al.
Publicado: (2009)

The serine‐threonine kinase PIM3 is an aldosterone‐regulated protein in the distal nephron
por: Spirli, Alessia, et al.
Publicado: (2019)

Expression of the Testis-Specific Serine/Threonine Kinases Suggests Their Role in Spermiogenesis of Bay Scallop Argopecten irradians
por: Xue, Xinru, et al.
Publicado: (2021)

Prediction of prkC-mediated protein serine/threonine phosphorylation sites for bacteria
por: Zhang, Qing-bin, et al.
Publicado: (2018)

Contribution of Eukaryotic-Type Serine/Threonine Kinase to Stress Response and Virulence of Streptococcus suis
por: Zhu, Haodan, et al.
Publicado: (2014)

Salmonella Effector SteE Converts the Mammalian Serine/Threonine Kinase GSK3 into a Tyrosine Kinase to Direct Macrophage Polarization
por: Panagi, Ioanna, et al.
Publicado: (2020)

Broad phosphorylation mediated by testis-specific serine/threonine kinases contributes to spermiogenesis and male fertility
por: Zhang, Xuedi, et al.
Publicado: (2023)

The Eukaryote-Like Serine/Threonine Kinase STK Regulates the Growth and Metabolism of Zoonotic Streptococcus suis
por: Zhang, Chunyan, et al.
Publicado: (2017)

Receptor-interacting serine/threonine-protein kinase 1 promotes the progress and lymph metastasis of gallbladder cancer
por: Zhu, Guangwei, et al.
Publicado: (2019)

Regulation of Hemolysin Expression and Virulence of Staphylococcus aureus by a Serine/Threonine Kinase and Phosphatase
por: Burnside, Kellie, et al.
Publicado: (2010)

Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases
por: Karpov, Pavel A, et al.
Publicado: (2010)

Cross-phosphorylation of bacterial serine/threonine and tyrosine protein kinases on key regulatory residues
por: Shi, Lei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dl4vfbe1h6krjcbfr3tedn5k2s