MAP4K4 promotes ovarian cancer metastasis through diminishing ADAM10-dependent N-cadherin cleavage

Peritoneal metastasis is a key feature of advanced ovarian cancer, but the critical protein required for ovarian cancer metastasis and progression is yet to be defined. Thus, an unbiased high throughput and in-depth study is warranted to unmask the mechanism. Transcriptomic sequencing of paired prim...

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Detalles Bibliográficos
Autores principales: Chen, Kelie, Yuan, Xiaoyu, Wang, Shengchao, Zheng, Fang, Fu, Zhiqin, Shen, Zhangjin, Cheng, Xiaodong, Wang, Yuwei, Tang, Song, Ni, Heng, Wang, Fang, Lu, Guang, Wu, Yihua, Xia, Dajing, Lu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154218/
https://www.ncbi.nlm.nih.gov/pubmed/36922678
http://dx.doi.org/10.1038/s41388-023-02650-5

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