Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain

The diversity of cell types is a challenge for quantifying aging and its reversal. Here we develop ‘aging clocks’ based on single-cell transcriptomics to characterize cell-type-specific aging and rejuvenation. We generated single-cell transcriptomes from the subventricular zone neurogenic region of...

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Detalles Bibliográficos
Autores principales: Buckley, Matthew T., Sun, Eric D., George, Benson M., Liu, Ling, Schaum, Nicholas, Xu, Lucy, Reyes, Jaime M., Goodell, Margaret A., Weissman, Irving L., Wyss-Coray, Tony, Rando, Thomas A., Brunet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154228/
https://www.ncbi.nlm.nih.gov/pubmed/37118510
http://dx.doi.org/10.1038/s43587-022-00335-4

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