Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells

Aging is accompanied by a general decline in the function of many cellular pathways. However, whether these are causally or functionally interconnected remains elusive. Here, we study the effect of mitochondrial–nuclear communication on stem cell aging. We show that aged mesenchymal stem cells exhib...

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Detalles Bibliográficos
Autores principales: Pouikli, Andromachi, Parekh, Swati, Maleszewska, Monika, Nikopoulou, Chrysa, Baghdadi, Maarouf, Tripodi, Ignacio, Folz-Donahue, Kat, Hinze, Yvonne, Mesaros, Andrea, Hoey, David, Giavalisco, Patrick, Dowell, Robin, Partridge, Linda, Tessarz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154229/
https://www.ncbi.nlm.nih.gov/pubmed/37117628
http://dx.doi.org/10.1038/s43587-021-00105-8

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