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Chronic in vivo imaging defines age-dependent alterations of neurogenesis in the mouse hippocampus
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian hippocampus(1). Advancing age leads to a decline in neurogenesis, which is associated with impaired cognition(2,3). The cellular mechanisms causing reduced neurogenesis with advancing age remain largely unknown. We geneti...
Autores principales: | Wu, Yicheng, Bottes, Sara, Fisch, Roberto, Zehnder, Cinzia, Cole, John Darby, Pilz, Gregor-Alexander, Helmchen, Fritjof, Simons, Benjamin D., Jessberger, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154232/ https://www.ncbi.nlm.nih.gov/pubmed/37117787 http://dx.doi.org/10.1038/s43587-023-00370-9 |
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