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Chronic in vivo imaging defines age-dependent alterations of neurogenesis in the mouse hippocampus

Neural stem cells (NSCs) generate new neurons throughout life in the mammalian hippocampus(1). Advancing age leads to a decline in neurogenesis, which is associated with impaired cognition(2,3). The cellular mechanisms causing reduced neurogenesis with advancing age remain largely unknown. We geneti...

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Detalles Bibliográficos
Autores principales: Wu, Yicheng, Bottes, Sara, Fisch, Roberto, Zehnder, Cinzia, Cole, John Darby, Pilz, Gregor-Alexander, Helmchen, Fritjof, Simons, Benjamin D., Jessberger, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154232/
https://www.ncbi.nlm.nih.gov/pubmed/37117787
http://dx.doi.org/10.1038/s43587-023-00370-9

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