Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types

Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decline are modifiable or even reversible. To better un...

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Detalles Bibliográficos
Autores principales: Ximerakis, Methodios, Holton, Kristina M., Giadone, Richard M., Ozek, Ceren, Saxena, Monika, Santiago, Samara, Adiconis, Xian, Dionne, Danielle, Nguyen, Lan, Shah, Kavya M., Goldstein, Jill M., Gasperini, Caterina, Gampierakis, Ioannis A., Lipnick, Scott L., Simmons, Sean K., Buchanan, Sean M., Wagers, Amy J., Regev, Aviv, Levin, Joshua Z., Rubin, Lee L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154248/
https://www.ncbi.nlm.nih.gov/pubmed/37118429
http://dx.doi.org/10.1038/s43587-023-00373-6

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