Unique progerin C-terminal peptide ameliorates Hutchinson–Gilford progeria syndrome phenotype by rescuing BUBR1

An accumulating body of evidence indicates an association between mitotic defects and the aging process in Hutchinson–Gilford progeria syndrome (HGPS), which is a premature aging disease caused by progerin accumulation. Here, we found that BUBR1, a core component of the spindle assembly checkpoint,...

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Detalles Bibliográficos
Autores principales: Zhang, Na, Hu, Qianying, Sui, Tingting, Fu, Lu, Zhang, Xinglin, Wang, Yu, Zhu, Xiaojuan, Huang, Baiqu, Lu, Jun, Li, Zhanjun, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154249/
https://www.ncbi.nlm.nih.gov/pubmed/37118121
http://dx.doi.org/10.1038/s43587-023-00361-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154249/
https://www.ncbi.nlm.nih.gov/pubmed/37118121
http://dx.doi.org/10.1038/s43587-023-00361-w

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