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KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress
In response to stress, cells make a critical decision to arrest or undergo apoptosis, mediated in large part by the tumor suppressor p53. Yet the mechanisms of these cell fate decisions remain largely unknown, particularly in normal cells. Here, we define an incoherent feed-forward loop in non-trans...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154356/ https://www.ncbi.nlm.nih.gov/pubmed/37130837 http://dx.doi.org/10.1038/s41419-023-05731-1 |