KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress

In response to stress, cells make a critical decision to arrest or undergo apoptosis, mediated in large part by the tumor suppressor p53. Yet the mechanisms of these cell fate decisions remain largely unknown, particularly in normal cells. Here, we define an incoherent feed-forward loop in non-trans...

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Detalles Bibliográficos
Autores principales: Yang, Yizeng, Bhargava, Dharmendra, Chen, Xiao, Zhou, Taicheng, Dursuk, Gizem, Jiang, Wenpeng, Wang, Jinshen, Zong, Zhen, Katz, Sharyn I., Lomberk, Gwen A., Urrutia, Raul A., Katz, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154356/
https://www.ncbi.nlm.nih.gov/pubmed/37130837
http://dx.doi.org/10.1038/s41419-023-05731-1

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