Critically short telomeres derepress retrotransposons to promote genome instability in embryonic stem cells

Telomeres, at the ends of chromosomes, protect chromosomes from fusion and preserve genomic stability. However, the molecular mechanisms underlying telomere attrition-induced genome instability remain to be understood. We systematically analyzed the expression of retrotransposons and performed genom...

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Detalles Bibliográficos
Autores principales: Zhao, Nannan, Yin, Guoxing, Liu, Chun, Zhang, Weiyu, Shen, Yang, Wang, Dan, Lin, Zhenzhen, Yang, Jiao, Mao, Jian, Guo, Renpeng, Zhang, Yongwang, Wang, Feng, Liu, Zhe, Lu, Xinyi, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154409/
https://www.ncbi.nlm.nih.gov/pubmed/37130870
http://dx.doi.org/10.1038/s41421-023-00538-y

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