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Microglia and astrocytes mediate synapse engulfment in a MER tyrosine kinase-dependent manner after traumatic brain injury

Recent studies have shown that microglia/macrophages and astrocytes can mediate synaptic phagocytosis through the MER proto-oncokinase in developmental or stroke models, but it is unclear whether the same mechanism is also active in traumatic brain injury. In this study, we established a mouse model...

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Detalles Bibliográficos
Autores principales: Shen, Hui, Shi, Xiao-Jing, Qi, Lin, Wang, Cheng, Mamtilahun, Muyassar, Zhang, Zhi-Jun, Chung, Won-Suk, Yang, Guo-Yuan, Tang, Yao-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154480/
https://www.ncbi.nlm.nih.gov/pubmed/36751804
http://dx.doi.org/10.4103/1673-5374.363187