Cargando…

Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson’s disease

Use of glucagon-like peptide-1 receptor agonist or dipeptidyl peptidase 4 inhibitor has been shown to lower the incidence of Parkinson’s disease in patients with diabetes mellitus. Therefore, using these two treatments may help treat Parkinson’s disease. To further investigate the mechanisms of acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Hai-Yang, Sun, Tong, Wang, Zhen, Li, Hong, Xu, Duo, An, Jing, Wen, Lu-Lu, Li, Jia-Yi, Li, Wen, Feng, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154509/ https://www.ncbi.nlm.nih.gov/pubmed/36751811 http://dx.doi.org/10.4103/1673-5374.360242

Ejemplares similares

Exendin-4 attenuates pain-induced cognitive impairment by alleviating hippocampal neuroinflammation in a rat model of spinal nerve ligation
por: Cui, Shan-Shan, et al.
Publicado: (2020)

Exendin-4 for Parkinson's disease
por: Esparza-Salazar, Felipe de Jesús, et al.
Publicado: (2021)

DPP‐4 Inhibitor Linagliptin Attenuates Aβ‐induced Cytotoxicity through Activation of AMPK in Neuronal Cells
por: Kornelius, Edy, et al.
Publicado: (2015)

Targeting Persistent Neuroinflammation after Hypoxic-Ischemic Encephalopathy—Is Exendin-4 the Answer?
por: Zhou, Kelly Q., et al.
Publicado: (2022)

Effect of the GLP-1 Analog Exendin-4 and Oxaliplatin on Intrahepatic Cholangiocarcinoma Cell Line and Mouse Model
por: Chen, Ben-Dong, et al.
Publicado: (2013)

Microglial cGAS drives neuroinflammation in the MPTP mouse models of Parkinson's disease
por: Ma, Chunmei, et al.
Publicado: (2023)

NR4A1 agonist cytosporone B attenuates neuroinflammation in a mouse model of multiple sclerosis
por: Yu, Hai-Zhen, et al.
Publicado: (2022)

Exendin-4 attenuates atherosclerosis progression via controlling hematopoietic stem/progenitor cell proliferation
por: Yan, Cen, et al.
Publicado: (2023)

Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson’s Disease Models
por: Yang, Hanyu, et al.
Publicado: (2020)

Combined Treatment with Exendin-4 and Metformin Attenuates Prostate Cancer Growth
por: Tsutsumi, Yoko, et al.
Publicado: (2015)

Exendin-4 Attenuates Hepatic Steatosis by Promoting the Autophagy-Lysosomal Pathway
por: Yu, Hsin-Hsien, et al.
Publicado: (2022)

Duzhong Fang Attenuates the POMC-Derived Neuroinflammation in Parkinsonian Mice
por: Li, Lili, et al.
Publicado: (2021)

Repositioning of Hypoglycemic Drug Linagliptin for Cancer Treatment
por: Li, Yong, et al.
Publicado: (2020)

Neuroprotective effects of linagliptin in a rotenone-induced rat model of Parkinson's disease
por: Abhangi, Kinjal V, et al.
Publicado: (2022)

Resveratrol attenuates neurological deficit and neuroinflammation following intracerebral hemorrhage
por: Cai, Jia-Chen, et al.
Publicado: (2018)

Linagliptin Regulates the Mitochondrial Respiratory Reserve to Alter Platelet Activation and Arterial Thrombosis
por: Li, Yi, et al.
Publicado: (2020)

Exendin-4 antagonizes Aβ1-42-induced attenuation of spatial learning and memory ability
por: Wang, Xiaohui, et al.
Publicado: (2016)

MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease
por: Geng, Lu, et al.
Publicado: (2023)

Exendin-4 Pretreatment Attenuates Kainic Acid-Induced Hippocampal Neuronal Death
por: Ahn, Yu-Jeong, et al.
Publicado: (2021)

The GLP-1R Agonist Exendin-4 Attenuates Hyperglycemia-Induced Chemoresistance in Human Endometrial Cancer Cells Through ROS-Mediated Mitochondrial Pathway
por: Zhang, Yu, et al.
Publicado: (2021)

The clinical application of linagliptin in Asians
por: Cao, Chu-qing, et al.
Publicado: (2015)

Linagliptin: from bench to bedside
por: Doupis, John
Publicado: (2014)

Dipeptidyl peptidase-4 inhibitor linagliptin attenuates neointima formation after vascular injury
por: Terawaki, Yuichi, et al.
Publicado: (2014)

The phosphodiesterase inhibitor, ibudilast, attenuates neuroinflammation in the MPTP model of Parkinson’s disease
por: Schwenkgrub, Joanna, et al.
Publicado: (2017)

Association between Parkinson’s Disease and Diabetes Mellitus: From Epidemiology, Pathophysiology and Prevention to Treatment
por: Yu, Haiyang, et al.
Publicado: (2022)

Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway
por: Wei, Hong, et al.
Publicado: (2019)

Tetrahydroxystilbene Glucoside Attenuates Neuroinflammation through the Inhibition of Microglia Activation
por: Zhang, Feng, et al.
Publicado: (2013)

LRRK2 Kinase Inhibition Attenuates Neuroinflammation and Cytotoxicity in Animal Models of Alzheimer’s and Parkinson’s Disease-Related Neuroinflammation
por: Mutti, Veronica, et al.
Publicado: (2023)

Icaritin Provides Neuroprotection in Parkinson’s Disease by Attenuating Neuroinflammation, Oxidative Stress, and Energy Deficiency
por: Wu, Hao, et al.
Publicado: (2021)

Coriandrum sativum attenuates microglia mediated neuroinflammation and MPTP-induced behavioral and oxidative changes in Parkinson’s disease mouse model
por: Koppula, Sushruta, et al.
Publicado: (2021)

Whole Body Vibration Attenuates Brain Damage and Neuroinflammation Following Experimental Traumatic Brain Injury
por: Chen, Tao, et al.
Publicado: (2022)

Muscone with Attenuation of Neuroinflammation and Oxidative Stress Exerts Antidepressant-Like Effect in Mouse Model of Chronic Restraint Stress
por: Liu, Hua, et al.
Publicado: (2022)

Linagliptin Protects against Endotoxin-Induced Acute Kidney Injury in Rats by Decreasing Inflammatory Cytokines and Reactive Oxygen Species
por: Wu, Tsung-Jui, et al.
Publicado: (2021)

Incorrect description of mode of excretion of linagliptin
por: Woerle, Hans-Juergen, et al.
Publicado: (2010)

Acute Kidney Injury Associated with Linagliptin
por: Nandikanti, Deepak K., et al.
Publicado: (2016)

Linagliptin-Associated Alopecia and Bullous Pemphigoid
por: Someili, Ali, et al.
Publicado: (2019)

Botulinum neurotoxin A ameliorates depressive-like behavior in a reserpine-induced Parkinson’s disease mouse model via suppressing hippocampal microglial engulfment and neuroinflammation
por: Li, Yang, et al.
Publicado: (2023)

Analytical Enantio-Separation of Linagliptin in Linagliptin and Metformin HCl Dosage Forms by Applying Two-Level Factorial Design
por: Jadhav, Sushant B., et al.
Publicado: (2016)

Phosphorylated α-synuclein aggregated in Schwann cells exacerbates peripheral neuroinflammation and nerve dysfunction in Parkinson’s disease through TLR2/NF-κB pathway
por: Sun, Li, et al.
Publicado: (2021)

Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis
por: Kim, Ji-Won, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n4olh70bq2jrstmlrgreg0bv93