Fortuitous somatic mutations during antibody evolution endow broad neutralization against SARS-CoV-2 Omicron variants

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Striking antibody evasion by emerging circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants drives the identification of broadly neutralizing antibodies (bNAbs). However, how a bNAb acquires increased neutralization breadth during antibody evolution is still elusive. Here...

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Detalles Bibliográficos
Autores principales: Wu, Jianbo, Chen, Zhenguo, Gao, Yidan, Wang, Zegen, Wang, Jiarong, Chiang, Bing-Yu, Zhou, Yunjiao, Han, Yuru, Zhan, Wuqiang, Xie, Minxiang, Jiang, Weiyu, Zhang, Xiang, Hao, Aihua, Xia, Anqi, He, Jiaying, Xue, Song, Mayer, Christian T., Wu, Fan, Wang, Bin, Zhang, Lunan, Sun, Lei, Wang, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154539/
https://www.ncbi.nlm.nih.gov/pubmed/37178120
http://dx.doi.org/10.1016/j.celrep.2023.112503
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