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Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort

OBJECTIVE: Environmental exposures may have greater predictive power for type 2 diabetes than polygenic scores (PGS). Studies examining environmental risk factors, however, have included only individuals with European ancestry, limiting the applicability of results. We conducted an exposome-wide ass...

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Detalles Bibliográficos
Autores principales: Akhtari, Farida S., Lloyd, Dillon, Burkholder, Adam, Tong, Xiaoran, House, John S., Lee, Eunice Y., Buse, John, Schurman, Shepherd H., Fargo, David C., Schmitt, Charles P., Hall, Janet, Motsinger-Reif, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154656/
https://www.ncbi.nlm.nih.gov/pubmed/36383734
http://dx.doi.org/10.2337/dc22-0295