Cargando…

UXT at the crossroads of cell death, immunity and neurodegenerative diseases

The ubiquitous expressed transcript (UXT), a member of the prefoldin-like protein family, modulates regulated cell death (RCD) such as apoptosis and autophagy-mediated cell death through nuclear factor-κB (NF-κB), tumor necrosis factor-α (TNF-α), P53, P62, and methylation, and is involved in the reg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Pengzhe, Mo, Shaojian, Wang, Zhengwang, Xu, Jiale, Fu, Xifeng, Tian, Yanzhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154696/ https://www.ncbi.nlm.nih.gov/pubmed/37152054 http://dx.doi.org/10.3389/fonc.2023.1179947

Ejemplares similares

UXT is required for spermatogenesis in mice
por: Schafler, Eric D., et al.
Publicado: (2018)

UXT potentiates angiogenesis by attenuating Notch signaling
por: Zhou, Yi, et al.
Publicado: (2015)

Overexpressing PLOD Family Genes Predict Poor Prognosis in Pancreatic Cancer
por: Zhang, Jing, et al.
Publicado: (2022)

Physical activity, sedentary behavior and pancreatitis risk: Mendelian randomization study
por: Ling, Ruiqi, et al.
Publicado: (2023)

Prostate-specific loss of UXT promotes cancer progression
por: Wang, Yu, et al.
Publicado: (2019)

UXT is a novel regulatory factor of regulatory T cells associated with Foxp3
por: Li, Weina, et al.
Publicado: (2014)

The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway
por: Spagnol, Valentine, et al.
Publicado: (2021)

Chemotherapy-Induced Tumor Cell Death at the Crossroads Between Immunogenicity and Immunotolerance: Focus on Acute Myeloid Leukemia
por: Ocadlikova, Darina, et al.
Publicado: (2019)

Serglycin: At the Crossroad of Inflammation and Malignancy
por: Korpetinou, Angeliki, et al.
Publicado: (2014)

UXT is a novel and essential cofactor in the NF-κB transcriptional enhanceosome
por: Sun, Shaogang, et al.
Publicado: (2007)

UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy
por: Yoon, Min Ji, et al.
Publicado: (2021)

Cdc13 at a crossroads of telomerase action
por: Churikov, Dmitri, et al.
Publicado: (2013)

Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation
por: Pan, Mingyu, et al.
Publicado: (2020)

Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?
por: Gonfloni, Stefania, et al.
Publicado: (2012)

Clonal Hematopoiesis at the Crossroads of Inflammatory Bowel Diseases and Hematological Malignancies: A Biological Link?
por: Cumbo, Cosimo, et al.
Publicado: (2022)

Brucella infection-induced hemophagocytic syndrome with subsequent development of the probable vanishing bile duct syndrome: A case report and literature review
por: Xu, Musen, et al.
Publicado: (2023)

Ubiquitin at the crossroad of cell death and survival
por: Chen, Yu-Shan, et al.
Publicado: (2013)

XIAP at the crossroads of cell death and inflammation
por: Vucic, Domagoj
Publicado: (2018)

Sirtuins at the Crossroads between Mitochondrial Quality Control and Neurodegenerative Diseases: Structure, Regulation, Modifications, and Modulators
por: Xu, Hui, et al.
Publicado: (2023)

UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation
por: Huang, Yuefeng, et al.
Publicado: (2011)

14-3-3 Proteins Are on the Crossroads of Cancer, Aging, and Age-Related Neurodegenerative Disease
por: Fan, Xiaolan, et al.
Publicado: (2019)

c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases
por: Gutiérrez, Daniela A., et al.
Publicado: (2022)

Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer
por: Tomaselli, Daniela, et al.
Publicado: (2020)

Tumor Treating Fields: At the Crossroads Between Physics and Biology for Cancer Treatment
por: Carrieri, Francesca A., et al.
Publicado: (2020)

Endoplasmic Reticulum Stress Signaling in Plant Immunity—At the Crossroad of Life and Death
por: Kørner, Camilla J., et al.
Publicado: (2015)

The eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral Infections
por: Abbas, Wasim, et al.
Publicado: (2015)

Multifaceted WNT Signaling at the Crossroads Between Epithelial-Mesenchymal Transition and Autophagy in Glioblastoma
por: Coelho, Bárbara Paranhos, et al.
Publicado: (2020)

Mitochondria in cancer: at the crossroads of life and death
por: Fogg, Vanessa C., et al.
Publicado: (2011)

Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways
por: Zilka, Norbert, et al.
Publicado: (2012)

Prognosis Analysis and Validation of m(6)A Signature and Tumor Immune Microenvironment in Glioma
por: Lin, Shaojian, et al.
Publicado: (2020)

Immune Response at the Crossroads of Atherosclerosis and Alzheimer's Disease
por: Stahr, Natalie, et al.
Publicado: (2022)

Construction and validation of a novel web-based nomogram for patients with lung cancer with bone metastasis: A real-world analysis based on the SEER database
por: Yin, Mengchen, et al.
Publicado: (2022)

At the Crossroads: Mechanisms of Apoptosis and Autophagy in Cell Life and Death
por: Shliapina, V. L., et al.
Publicado: (2021)

Supportive care of neurodegenerative patients
por: Armitage, A. E., et al.
Publicado: (2023)

Immunomodulatory effects of microbiota-derived metabolites at the crossroad of neurodegenerative diseases and viral infection: network-based bioinformatics insights
por: Onisiforou, Anna, et al.
Publicado: (2022)

At the Crossroads of Life and Death: The Proteins That Influence Cell Fate Decisions
por: Dhokia, Vinesh, et al.
Publicado: (2022)

Adaptive immunity at the crossroads of autophagy and metabolism
por: Metur, Shree Padma, et al.
Publicado: (2021)

UXT, a novel MDMX-binding protein, promotes glycolysis by mitigating p53-mediated restriction of NF-κB activity
por: Qi, Min, et al.
Publicado: (2015)

MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape
por: Lemma, Roza Berhanu, et al.
Publicado: (2023)

Brain Development and Akt Signaling: the Crossroads of Signaling Pathway and Neurodevelopmental Diseases
por: Wang, Long, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tpl5i76lpn2cek3optrnn71evi