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Positron Emission Tomography Assessments of Phosphodiesterase 10A in Patients With Schizophrenia

BACKGROUND AND HYPOTHESIS: Phosphodiesterase 10A (PDE10A) is a highly expressed enzyme in the basal ganglia, where cortical glutamatergic and midbrain dopaminergic inputs are integrated. Therapeutic PDE10A inhibition effects on schizophrenia have been reported previously, but the status of this mole...

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Detalles Bibliográficos
Autores principales:	Kubota, Manabu, Takahata, Keisuke, Matsuoka, Kiwamu, Sano, Yasunori, Yamamoto, Yasuharu, Tagai, Kenji, Tarumi, Ryosuke, Suzuki, Hisaomi, Kurose, Shin, Nakajima, Shinichiro, Shiwaku, Hiroki, Seki, Chie, Kawamura, Kazunori, Zhang, Ming-Rong, Takahashi, Hidehiko, Takado, Yuhei, Higuchi, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Regular Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154699/ https://www.ncbi.nlm.nih.gov/pubmed/36458958 http://dx.doi.org/10.1093/schbul/sbac181

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