Increased sinusoidal pressure impairs liver endothelial mechanosensing, uncovering novel biomarkers of portal hypertension

BACKGROUND & AIMS: Portal hypertension (PH) is a frequent and severe clinical syndrome associated with chronic liver disease. Considering the mechanobiological effects of hydrostatic pressure and shear stress on endothelial cells, we hypothesised that PH might influence the phenotype of liver si...

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Detalles Bibliográficos
Autores principales: Ortega-Ribera, Martí, Gibert-Ramos, Albert, Abad-Jordà, Laia, Magaz, Marta, Téllez, Luis, Paule, Lorena, Castillo, Elisa, Pastó, Raül, de Souza Basso, Bruno, Olivas, Pol, Orts, Lara, Lozano, Juan José, Villa, Rosa, Bosch, Jaime, Albillos, Agustín, García-Pagán, Joan Carles, Gracia-Sancho, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154975/
https://www.ncbi.nlm.nih.gov/pubmed/37151732
http://dx.doi.org/10.1016/j.jhepr.2023.100722

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