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The Relationship between Protein–Protein Interactions and Liquid–Liquid Phase Separation for Monoclonal Antibodies
[Image: see text] Being able to predict and control concentrated solution properties for solutions of monoclonal antibodies (mAbs) is critical for developing therapeutic formulations. At higher protein concentrations, undesirable solution properties include high viscosities, opalescence, particle fo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155204/ https://www.ncbi.nlm.nih.gov/pubmed/37039349 http://dx.doi.org/10.1021/acs.molpharmaceut.3c00090 |