The Relationship between Protein–Protein Interactions and Liquid–Liquid Phase Separation for Monoclonal Antibodies

[Image: see text] Being able to predict and control concentrated solution properties for solutions of monoclonal antibodies (mAbs) is critical for developing therapeutic formulations. At higher protein concentrations, undesirable solution properties include high viscosities, opalescence, particle fo...

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Detalles Bibliográficos
Autores principales: Sibanda, Nicole, Shanmugam, Ramesh Kumar, Curtis, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155204/
https://www.ncbi.nlm.nih.gov/pubmed/37039349
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00090

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