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Evaluation of the possible association of PDCD-1 and LAG3 gene polymorphisms with hepatocellular carcinoma risk

PURPOSE: Programmed death-1 (PDCD-1) and lymphocyte activating 3 (LAG3), two important immunosuppressive molecules, play crucial roles in immune escape of tumor cells. This study evaluated the effects of PDCD-1 (rs10204525 and rs36084323), and LAG3 (rs870849 and rs1882545) gene polymorphisms on hepa...

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Detalles Bibliográficos
Autores principales: Wei, Jiankai, Liao, Zhangxiu, Tao, Ying, Liu, Shuaiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155321/
https://www.ncbi.nlm.nih.gov/pubmed/37131179
http://dx.doi.org/10.1186/s12920-023-01526-7