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Integrative multi-omics analysis depicts the methylome and hydroxymethylome in recurrent bladder cancers and identifies biomarkers for predicting PD-L1 expression
BACKGROUND: Urinary bladder cancer (UBC) is a common malignancy of the urinary tract; however, the mechanism underlying its high recurrence and responses to immunotherapy remains unclear, making clinical outcome predictions difficult. Epigenetic alterations, especially DNA methylation, play importan...
Autores principales: | Shi, Zhen-Duo, Han, Xiao-Xiao, Song, Zi-Jian, Dong, Yang, Pang, Kun, Wang, Xin-Lei, Liu, Xin-Yu, Lu, Hao, Xu, Guang-Zhi, Hao, Lin, Dong, Bing-Zheng, Liang, Qing, Wu, Xiao-Ke, Han, Cong-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155358/ https://www.ncbi.nlm.nih.gov/pubmed/37138354 http://dx.doi.org/10.1186/s40364-023-00488-3 |
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