Astrocytic CXCL5 hinders microglial phagocytosis of myelin debris and aggravates white matter injury in chronic cerebral ischemia

BACKGROUND: Chronic cerebral ischemia induces white matter injury (WMI) contributing to cognitive decline. Both astrocytes and microglia play vital roles in the demyelination and remyelination processes, but the underlying mechanism remains unclear. This study aimed to explore the influence of the c...

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Detalles Bibliográficos
Autores principales: Cao, Qian, Chen, Jian, Zhang, Zhi, Shu, Shu, Qian, Yi, Yang, Lixuan, Xu, Lushan, Zhang, Yuxin, Bao, Xinyu, Xia, Shengnan, Yang, Haiyan, Xu, Yun, Qiu, Shuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155379/
https://www.ncbi.nlm.nih.gov/pubmed/37138312
http://dx.doi.org/10.1186/s12974-023-02780-3

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