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Efficacy and safety of human umbilical cord-derived mesenchymal stem cells (hUC-MSC PLEB001) for the treatment of grade II–IV steroid-refractory acute graft-versus-host disease: a study protocol for a multicenter, randomized, double-blind, placebo-controlled, phase II trial

BACKGROUND: Systemic corticosteroid therapy failure is quite common in patients with newly diagnosed acute graft-versus-host disease (aGVHD). Growing evidence has suggested that mesenchymal stem cell (MSC) therapy could be a promising treatment option for aGVHD due to its distinctive immunomodulatin...

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Detalles Bibliográficos
Autores principales:	Yang, Donglin, Hou, Xiaoqiang, Qian, Kun, Li, Yuhang, Hu, Liangding, Li, Liang, Han, Mingzhe, Yao, Chen, Liu, Daihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155385/ https://www.ncbi.nlm.nih.gov/pubmed/37138332 http://dx.doi.org/10.1186/s13063-023-07305-0

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