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PKM2/STAT1-mediated PD-L1 upregulation on neutrophils during sepsis promotes neutrophil organ accumulation by serving an anti-apoptotic role
BACKGROUND: Delayed neutrophil apoptosis during sepsis may impact neutrophil organ accumulation and tissue immune homeostasis. Elucidating the mechanisms underlying neutrophil apoptosis may help identify potential therapeutic targets. Glycolysis is critical to neutrophil activities during sepsis. Ho...
Autores principales: | Li, Yinjiaozhi, Tan, Ruoming, Li, Ranran, Tian, Rui, Liu, Zhaojun, Wang, Xiaoli, Chen, Erzhen, Pan, Tingting, Qu, Hongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155438/ https://www.ncbi.nlm.nih.gov/pubmed/37131151 http://dx.doi.org/10.1186/s12950-023-00341-2 |
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