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Genomic alterations of cerebrospinal fluid cell-free DNA in leptomeningeal metastases of gastric cancer

BACKGROUND: Leptomeningeal metastases (LM) were rare in gastric cancer (GC), and GC patients with LM (GCLM) generally suffer from poor prognosis. Nevertheless, the clinical utility of cerebrospinal fluid (CSF) circulating tumor DNA (ctDNA) was underinvestigated in GCLM. METHODS: We retrospectively s...

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Detalles Bibliográficos
Autores principales:	Chen, Xin, Bai, Kaixuan, Zhang, Yu, Xu, Yang, Huo, Yinghao, Wang, Sha, Zou, Yueli, Qi, Xuejiao, Guo, Rongyun, Ou, Qiuxiang, Liu, Dengxiang, Yin, Shaohua, Chen, Shubo, Bu, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155444/ https://www.ncbi.nlm.nih.gov/pubmed/37131253 http://dx.doi.org/10.1186/s12967-023-04077-8

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