Bidirectional Mendelian Randomisation Analysis Provides Evidence for the Causal Involvement of Dysregulation of CXCL9, CCL11 and CASP8 in the Pathogenesis of Ulcerative Colitis

BACKGROUND AND AIMS: Systemic inflammation is well recognised to be associated with ulcerative colitis [UC], but whether these effects are causal or consequential remains unclear. We aimed to define potential causal relationship of cytokine dysregulation with different tiers of evidence. METHODS: We...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Zhou, Yajing, Sun, Yuhao, Yuan, Shuai, Kalla, Rahul, Sun, Jing, Zhao, Jianhui, Wang, Lijuan, Chen, Xuejie, Zhou, Xuan, Dai, Siqi, Zhang, Yu, Ho, Gwo-tzer, Xia, Dajing, Cao, Qian, Liu, Zhanju, Larsson, Susanna C, Wang, Xiaoyan, Ding, Kefeng, Halfvarson, Jonas, Li, Xue, Theodoratou, Evropi, Satsangi, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155748/
https://www.ncbi.nlm.nih.gov/pubmed/36576886
http://dx.doi.org/10.1093/ecco-jcc/jjac191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155748/
https://www.ncbi.nlm.nih.gov/pubmed/36576886
http://dx.doi.org/10.1093/ecco-jcc/jjac191

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