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Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis
Background Gastric cancer is one of the most common cancers and a leading cause of death worldwide. Most cases of gastric cancer are diagnosed at an advanced stage when no definitive treatment is available leading to an overall declined survival rate. In this study, we aimed to investigate the survi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155757/ https://www.ncbi.nlm.nih.gov/pubmed/37153312 http://dx.doi.org/10.7759/cureus.37064 |
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author | Pradhan, Smruti Priyambada Agarwala, Sunil Sahoo, Jyotiranjan Pradhan, Sukant Kumar Jena, Shubharanjan Satpathy, Nancy Epari, Venkatarao |
author_facet | Pradhan, Smruti Priyambada Agarwala, Sunil Sahoo, Jyotiranjan Pradhan, Sukant Kumar Jena, Shubharanjan Satpathy, Nancy Epari, Venkatarao |
author_sort | Pradhan, Smruti Priyambada |
collection | PubMed |
description | Background Gastric cancer is one of the most common cancers and a leading cause of death worldwide. Most cases of gastric cancer are diagnosed at an advanced stage when no definitive treatment is available leading to an overall declined survival rate. In this study, we aimed to investigate the survival rate of gastric cancer patients admitted to our tertiary care center and determined the relationship between sociodemographic and clinicopathological characteristics with mortality. Methodology Gastric cancer patients treated between January 2019 and December 2020 were included in this retrospective study. The clinicopathological and demographic data of 275 gastric cancer patients were analyzed. The Kaplan-Meier method was used to calculate the overall survival of gastric cancer patients. The Kaplan-Meier log-rank test was used to calculate the difference. Results The mean survival of gastric cancer patients was 20.10 months (95% confidence interval = 19.20-21.03). Deaths were higher among stage III (42.6%) and stage IV (36.1%) patients compared to stage I (1.6%) and stage II (19.7%) patients. Mortality was significantly higher (70.5%) in patients without surgery. Conclusions The mean survival in our study setting is lower and is associated with the pathological stage of the disease, surgical intervention, and patients presenting with other gastrointestinal symptoms. A lower survival rate can be attributed to late diagnosis. |
format | Online Article Text |
id | pubmed-10155757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-101557572023-05-04 Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis Pradhan, Smruti Priyambada Agarwala, Sunil Sahoo, Jyotiranjan Pradhan, Sukant Kumar Jena, Shubharanjan Satpathy, Nancy Epari, Venkatarao Cureus General Surgery Background Gastric cancer is one of the most common cancers and a leading cause of death worldwide. Most cases of gastric cancer are diagnosed at an advanced stage when no definitive treatment is available leading to an overall declined survival rate. In this study, we aimed to investigate the survival rate of gastric cancer patients admitted to our tertiary care center and determined the relationship between sociodemographic and clinicopathological characteristics with mortality. Methodology Gastric cancer patients treated between January 2019 and December 2020 were included in this retrospective study. The clinicopathological and demographic data of 275 gastric cancer patients were analyzed. The Kaplan-Meier method was used to calculate the overall survival of gastric cancer patients. The Kaplan-Meier log-rank test was used to calculate the difference. Results The mean survival of gastric cancer patients was 20.10 months (95% confidence interval = 19.20-21.03). Deaths were higher among stage III (42.6%) and stage IV (36.1%) patients compared to stage I (1.6%) and stage II (19.7%) patients. Mortality was significantly higher (70.5%) in patients without surgery. Conclusions The mean survival in our study setting is lower and is associated with the pathological stage of the disease, surgical intervention, and patients presenting with other gastrointestinal symptoms. A lower survival rate can be attributed to late diagnosis. Cureus 2023-04-03 /pmc/articles/PMC10155757/ /pubmed/37153312 http://dx.doi.org/10.7759/cureus.37064 Text en Copyright © 2023, Pradhan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | General Surgery Pradhan, Smruti Priyambada Agarwala, Sunil Sahoo, Jyotiranjan Pradhan, Sukant Kumar Jena, Shubharanjan Satpathy, Nancy Epari, Venkatarao Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis |
title | Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis |
title_full | Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis |
title_fullStr | Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis |
title_full_unstemmed | Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis |
title_short | Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis |
title_sort | survival of gastric cancer patients at a tertiary care hospital in eastern india: a retrospective data analysis |
topic | General Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155757/ https://www.ncbi.nlm.nih.gov/pubmed/37153312 http://dx.doi.org/10.7759/cureus.37064 |
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