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Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis

Background Gastric cancer is one of the most common cancers and a leading cause of death worldwide. Most cases of gastric cancer are diagnosed at an advanced stage when no definitive treatment is available leading to an overall declined survival rate. In this study, we aimed to investigate the survi...

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Autores principales: Pradhan, Smruti Priyambada, Agarwala, Sunil, Sahoo, Jyotiranjan, Pradhan, Sukant Kumar, Jena, Shubharanjan, Satpathy, Nancy, Epari, Venkatarao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155757/
https://www.ncbi.nlm.nih.gov/pubmed/37153312
http://dx.doi.org/10.7759/cureus.37064
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author Pradhan, Smruti Priyambada
Agarwala, Sunil
Sahoo, Jyotiranjan
Pradhan, Sukant Kumar
Jena, Shubharanjan
Satpathy, Nancy
Epari, Venkatarao
author_facet Pradhan, Smruti Priyambada
Agarwala, Sunil
Sahoo, Jyotiranjan
Pradhan, Sukant Kumar
Jena, Shubharanjan
Satpathy, Nancy
Epari, Venkatarao
author_sort Pradhan, Smruti Priyambada
collection PubMed
description Background Gastric cancer is one of the most common cancers and a leading cause of death worldwide. Most cases of gastric cancer are diagnosed at an advanced stage when no definitive treatment is available leading to an overall declined survival rate. In this study, we aimed to investigate the survival rate of gastric cancer patients admitted to our tertiary care center and determined the relationship between sociodemographic and clinicopathological characteristics with mortality. Methodology Gastric cancer patients treated between January 2019 and December 2020 were included in this retrospective study. The clinicopathological and demographic data of 275 gastric cancer patients were analyzed. The Kaplan-Meier method was used to calculate the overall survival of gastric cancer patients. The Kaplan-Meier log-rank test was used to calculate the difference. Results The mean survival of gastric cancer patients was 20.10 months (95% confidence interval = 19.20-21.03). Deaths were higher among stage III (42.6%) and stage IV (36.1%) patients compared to stage I (1.6%) and stage II (19.7%) patients. Mortality was significantly higher (70.5%) in patients without surgery. Conclusions The mean survival in our study setting is lower and is associated with the pathological stage of the disease, surgical intervention, and patients presenting with other gastrointestinal symptoms. A lower survival rate can be attributed to late diagnosis.
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spelling pubmed-101557572023-05-04 Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis Pradhan, Smruti Priyambada Agarwala, Sunil Sahoo, Jyotiranjan Pradhan, Sukant Kumar Jena, Shubharanjan Satpathy, Nancy Epari, Venkatarao Cureus General Surgery Background Gastric cancer is one of the most common cancers and a leading cause of death worldwide. Most cases of gastric cancer are diagnosed at an advanced stage when no definitive treatment is available leading to an overall declined survival rate. In this study, we aimed to investigate the survival rate of gastric cancer patients admitted to our tertiary care center and determined the relationship between sociodemographic and clinicopathological characteristics with mortality. Methodology Gastric cancer patients treated between January 2019 and December 2020 were included in this retrospective study. The clinicopathological and demographic data of 275 gastric cancer patients were analyzed. The Kaplan-Meier method was used to calculate the overall survival of gastric cancer patients. The Kaplan-Meier log-rank test was used to calculate the difference. Results The mean survival of gastric cancer patients was 20.10 months (95% confidence interval = 19.20-21.03). Deaths were higher among stage III (42.6%) and stage IV (36.1%) patients compared to stage I (1.6%) and stage II (19.7%) patients. Mortality was significantly higher (70.5%) in patients without surgery. Conclusions The mean survival in our study setting is lower and is associated with the pathological stage of the disease, surgical intervention, and patients presenting with other gastrointestinal symptoms. A lower survival rate can be attributed to late diagnosis. Cureus 2023-04-03 /pmc/articles/PMC10155757/ /pubmed/37153312 http://dx.doi.org/10.7759/cureus.37064 Text en Copyright © 2023, Pradhan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Pradhan, Smruti Priyambada
Agarwala, Sunil
Sahoo, Jyotiranjan
Pradhan, Sukant Kumar
Jena, Shubharanjan
Satpathy, Nancy
Epari, Venkatarao
Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis
title Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis
title_full Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis
title_fullStr Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis
title_full_unstemmed Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis
title_short Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis
title_sort survival of gastric cancer patients at a tertiary care hospital in eastern india: a retrospective data analysis
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155757/
https://www.ncbi.nlm.nih.gov/pubmed/37153312
http://dx.doi.org/10.7759/cureus.37064
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