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COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape

The COVID-19 outbreak has created disaster globally, and mankind is yet to come in terms with combating this global menace. Amid this turmoil, immunocompromised individuals like cancer patients exhibit dismal immune responses toward such infection. In order to treat cancer patients during such adver...

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Autores principales: Ghosh, Mrinal K, Kumar, Sunny, Ganguly, Kirat K, Ghosh, Pratyay, Tabassum, Shaheda, Basu, Bhaskar, Basu, Malini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155782/
http://dx.doi.org/10.2217/epi-2023-0052
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author Ghosh, Mrinal K
Kumar, Sunny
Ganguly, Kirat K
Ghosh, Pratyay
Tabassum, Shaheda
Basu, Bhaskar
Basu, Malini
author_facet Ghosh, Mrinal K
Kumar, Sunny
Ganguly, Kirat K
Ghosh, Pratyay
Tabassum, Shaheda
Basu, Bhaskar
Basu, Malini
author_sort Ghosh, Mrinal K
collection PubMed
description The COVID-19 outbreak has created disaster globally, and mankind is yet to come in terms with combating this global menace. Amid this turmoil, immunocompromised individuals like cancer patients exhibit dismal immune responses toward such infection. In order to treat cancer patients during such adverse situations, it is necessary to understand the phenomena that interlink these two diseased states. Modulation of host epigenetic landscape is a key hallmark of both cancer and viral infections, including COVID-19. Our review aims to shed light upon the interplay between COVID-19 and cancer, primarily through the genetic and epigenetic modulations of the gene expression profile, so as to design better therapeutic strategies in the near future.
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spelling pubmed-101557822023-05-04 COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape Ghosh, Mrinal K Kumar, Sunny Ganguly, Kirat K Ghosh, Pratyay Tabassum, Shaheda Basu, Bhaskar Basu, Malini Epigenomics Review The COVID-19 outbreak has created disaster globally, and mankind is yet to come in terms with combating this global menace. Amid this turmoil, immunocompromised individuals like cancer patients exhibit dismal immune responses toward such infection. In order to treat cancer patients during such adverse situations, it is necessary to understand the phenomena that interlink these two diseased states. Modulation of host epigenetic landscape is a key hallmark of both cancer and viral infections, including COVID-19. Our review aims to shed light upon the interplay between COVID-19 and cancer, primarily through the genetic and epigenetic modulations of the gene expression profile, so as to design better therapeutic strategies in the near future. Future Medicine Ltd 2023-05-02 2023-02 /pmc/articles/PMC10155782/ http://dx.doi.org/10.2217/epi-2023-0052 Text en © 2023 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Review
Ghosh, Mrinal K
Kumar, Sunny
Ganguly, Kirat K
Ghosh, Pratyay
Tabassum, Shaheda
Basu, Bhaskar
Basu, Malini
COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
title COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
title_full COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
title_fullStr COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
title_full_unstemmed COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
title_short COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
title_sort covid-19 and cancer: insights into their association and influence on genetic and epigenetic landscape
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155782/
http://dx.doi.org/10.2217/epi-2023-0052
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