Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain

In age-related neurodegenerative diseases, like Alzheimer’s and Parkinson’s, disease-specific proteins become aggregation-prone and form amyloid-like deposits. Depletion of SERF proteins ameliorates this toxic process in worm and human cell models for diseases. Whether SERF modifies amyloid patholog...

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Detalles Bibliográficos
Autores principales: Stroo, Esther, Janssen, Leen, Sin, Olga, Hogewerf, Wytse, Koster, Mirjam, Harkema, Liesbeth, Youssef, Sameh A, Beschorner, Natalie, Wolters, Anouk HG, Bakker, Bjorn, Becker, Lore, Garrett, Lilian, Marschall, Susan, Hoelter, Sabine M, Wurst, Wolfgang, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Thathiah, Amantha, Foijer, Floris, van de Sluis, Bart, van Deursen, Jan, Jucker, Matthias, de Bruin, Alain, Nollen, Ellen AA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155860/
https://www.ncbi.nlm.nih.gov/pubmed/37130781
http://dx.doi.org/10.26508/lsa.202201730

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