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Loss of Tbx3 in Mouse Eye Causes Retinal Angiogenesis Defects Reminiscent of Human Disease

PURPOSE: Familial exudative vitreoretinopathy (FEVR) and Norrie disease are examples of genetic disorders in which the retinal vasculature fails to fully form (hypovascular), leading to congenital blindness. While studying the role of a factor expressed during retinal development, T-box factor Tbx3,...

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Detalles Bibliográficos
Autores principales: Derbyshire, Mark L., Akula, Sruti, Wong, Austin, Rawlins, Karisa, Voura, Evelyn B., Brunken, William J., Zuber, Michael E., Fuhrmann, Sabine, Moon, Anne M., Viczian, Andrea S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155871/
https://www.ncbi.nlm.nih.gov/pubmed/37126314
http://dx.doi.org/10.1167/iovs.64.5.1