NK Cell Phenotype Is Associated With Response and Resistance to Daratumumab in Relapsed/Refractory Multiple Myeloma

The CD38-targeting antibody daratumumab has marked activity in multiple myeloma (MM). Natural killer (NK) cells play an important role during daratumumab therapy by mediating antibody-dependent cellular cytotoxicity via their FcγRIII receptor (CD16), but they are also rapidly decreased following ini...

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Detalles Bibliográficos
Autores principales: Verkleij, Christie P.M., Frerichs, Kristine A., Broekmans, Marloes E.C., Duetz, Carolien, O’Neill, Chloe A., Bruins, Wassilis S.C., Homan-Weert, Paola M., Minnema, Monique C., Levin, Mark-David, Broijl, Annemiek, Bos, Gerard M.J., Kersten, Marie José, Klein, Saskia K., Shikhagaie, Medya M., Casneuf, Tineke, Abraham, Yann, Smets, Tina, Vanhoof, Greet, Cortes-Selva, Diana, van Steenbergen, Laure, Ramos, Elena, Verona, Raluca I., Krevvata, Maria, Sonneveld, Pieter, Zweegman, Sonja, Mutis, Tuna, van de Donk, Niels W.C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155898/
https://www.ncbi.nlm.nih.gov/pubmed/37153876
http://dx.doi.org/10.1097/HS9.0000000000000881

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