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Engineering fluorescent protein chromophores with an internal reference for high-fidelity ratiometric G4 imaging in living cells
G-quadruplexes (G4s) are significant nucleic acid secondary structures formed by guanine-rich sequences. Many single-emission G4 fluorescent probes that are lit up by inhibiting intramolecular rotation have been reported. However, they are non-fluorescent unless structurally rigidified, making them...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155918/ https://www.ncbi.nlm.nih.gov/pubmed/37152256 http://dx.doi.org/10.1039/d3sc00022b |