Sperm morphological abnormalities in autosomal dominant polycystic kidney disease are associated with the Hippo signaling pathway via PC1

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary kidney disorder mostly caused by mutations in PKD1 or PKD2 genes. Here, we report thirteen ADPKD males with infertility and investigated the sperm morphological defects associated with PC1 disruption. METHODS: Targeted...

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Detalles Bibliográficos
Autores principales: Shi, Wei-Hui, Zhou, Zhi-Yang, Ye, Mu-Jin, Qin, Ning-Xin, Jiang, Zi-Ru, Zhou, Xuan-You, Xu, Nai-Xin, Cao, Xian-Lin, Chen, Song-Chang, Huang, He-Feng, Xu, Chen-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155925/
https://www.ncbi.nlm.nih.gov/pubmed/37152951
http://dx.doi.org/10.3389/fendo.2023.1130536

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