Cargando…

A predicted structure of NADPH Oxidase 1 identifies key components of ROS generation and strategies for inhibition

NADPH oxidase 1 (NOX1) is primarily expressed in epithelial cells and responsible for local generation of reactive oxygen species (ROS). By specifically manipulating the local redox microenvironment, NOX1 actively engages in epithelial immunity, especially in colorectal and pulmonary epithelia. To u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yezhou, Liang, Shiyu, Shi, Danfeng, Zhang, Yue, Bai, Chen, Ye, Richard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155968/ https://www.ncbi.nlm.nih.gov/pubmed/37134122 http://dx.doi.org/10.1371/journal.pone.0285206

Ejemplares similares

The Anorexigenic Effect of Serotonin Is Mediated by the Generation of NADPH Oxidase-Dependent ROS
por: Fang, Xin-Ling, et al.
Publicado: (2013)

From Flies to Men: ROS and the NADPH Oxidase in Phagocytes
por: Moghadam, Zohreh Mansoori, et al.
Publicado: (2021)

Silica particles cause NADPH oxidase–independent ROS generation and transient phagolysosomal leakage
por: Joshi, Gaurav N., et al.
Publicado: (2015)

Regulation of ROS signal transduction by NADPH oxidase 4 localization
por: Chen, Kai, et al.
Publicado: (2008)

Nrf2 regulates ROS production by mitochondria and NADPH oxidase
por: Kovac, Stjepana, et al.
Publicado: (2015)

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes
por: Daugaard, Mads, et al.
Publicado: (2013)

Coronatine Inhibits Stomatal Closure through Guard Cell-Specific Inhibition of NADPH Oxidase-Dependent ROS Production
por: Toum, Laila, et al.
Publicado: (2016)

Xanthohumol Induces ROS through NADPH Oxidase, Causes Cell Cycle Arrest and Apoptosis
por: Wang, Chun-Ming, et al.
Publicado: (2021)

Cross-Talk between NADPH Oxidase and Mitochondria: Role in ROS Signaling and Angiogenesis
por: Fukai, Tohru, et al.
Publicado: (2020)

Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis
por: Han, Jin, et al.
Publicado: (2022)

Intermedin in Paraventricular Nucleus Attenuates Ang II-Induced Sympathoexcitation through the Inhibition of NADPH Oxidase-Dependent ROS Generation in Obese Rats with Hypertension
por: Kang, Ying, et al.
Publicado: (2019)

NADPH Oxidase and Neurodegeneration
por: Hernandes, Marina S, et al.
Publicado: (2012)

ROS signaling by NADPH oxidase 5 modulates the proliferation and survival of prostate carcinoma cells
por: Höll, Monika, et al.
Publicado: (2015)

Peroxisomal polyamine oxidase and NADPH-oxidase cross-talk for ROS homeostasis which affects respiration rate in Arabidopsis thaliana
por: Andronis, Efthimios A., et al.
Publicado: (2014)

Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme
por: Katsuyama, Masato, et al.
Publicado: (2012)

Inhibition of NADPH Oxidase by Apocynin Attenuates Progression of Atherosclerosis
por: Kinkade, Kara, et al.
Publicado: (2013)

The Importance of Myeloperoxidase in Apocynin-Mediated NADPH Oxidase Inhibition
por: de Almeida, Ana Carolina, et al.
Publicado: (2012)

NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy
por: El Khoury, Mirella, et al.
Publicado: (2023)

Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation
por: Hatanaka, Elaine, et al.
Publicado: (2013)

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
por: Henríquez-Olguin, Carlos, et al.
Publicado: (2019)

Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats
por: Ding, Lei, et al.
Publicado: (2019)

tBHQ attenuates podocyte injury in diabetic nephropathy by inhibiting NADPH oxidase-derived ROS generation via the Nrf2/HO-1 signalling pathway
por: Liu, Ting, et al.
Publicado: (2022)

Polyamine Oxidase-Generated Reactive Oxygen Species in Plant Development and Adaptation: The Polyamine Oxidase—NADPH Oxidase Nexus
por: Benkő, Péter, et al.
Publicado: (2022)

NADPH Oxidases and Their Role in Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2020)

NADPH Oxidases in Pain Processing
por: Kallenborn-Gerhardt, Wiebke, et al.
Publicado: (2022)

NADPH Oxidases in Aortic Aneurysms
por: Salmon, Morgan
Publicado: (2022)

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
por: Weyemi, U, et al.
Publicado: (2012)

Identification of the NADPH Oxidase 4 Inhibiting Principle of Lycopus europaeus
por: Revoltella, Silvia, et al.
Publicado: (2018)

Specific inhibition of NADPH oxidase 2 modifies chronic epilepsy
por: Singh, Prince Kumar, et al.
Publicado: (2022)

NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy
por: Mustapha, Nik M., et al.
Publicado: (2010)

Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation
por: Kovac, S, et al.
Publicado: (2014)

Signaling Role of NADPH Oxidases in ROS-Dependent Host Cell Death Induced by Pathogenic Entamoeba histolytica
por: Lee, Young Ah, et al.
Publicado: (2022)

Duox is the primary NADPH oxidase responsible for ROS production during adult caudal fin regeneration in zebrafish
por: Chopra, Kunal, et al.
Publicado: (2023)

Involvement of NADPH oxidases in the Na/K‑ATPase/Src/ROS oxidant amplification loop in renal fibrosis
por: Zhang, Huimin, et al.
Publicado: (2023)

Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight Junctions
por: Rochfort, Keith D., et al.
Publicado: (2014)

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex
por: Kim, So Yeon, et al.
Publicado: (2017)

ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway
por: Chen, Zhida, et al.
Publicado: (2020)

Natural Compounds as Modulators of NADPH Oxidases
por: Maraldi, Tullia
Publicado: (2013)

NADPH Oxidases and Mitochondria in Vascular Senescence
por: Salazar, Gloria
Publicado: (2018)

NADPH oxidases: Current aspects and tools
por: Schröder, Katrin
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sr44neep1bq9fbfhs5imtviskr