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A predicted structure of NADPH Oxidase 1 identifies key components of ROS generation and strategies for inhibition

NADPH oxidase 1 (NOX1) is primarily expressed in epithelial cells and responsible for local generation of reactive oxygen species (ROS). By specifically manipulating the local redox microenvironment, NOX1 actively engages in epithelial immunity, especially in colorectal and pulmonary epithelia. To u...

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Detalles Bibliográficos
Autores principales:	Liu, Yezhou, Liang, Shiyu, Shi, Danfeng, Zhang, Yue, Bai, Chen, Ye, Richard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155968/ https://www.ncbi.nlm.nih.gov/pubmed/37134122 http://dx.doi.org/10.1371/journal.pone.0285206

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