Cargando…

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Cells respond to environmental cues by remodeling their inventories of multiprotein complexes. Cellular repertoires of SCF (SKP1-CUL1-F box protein) ubiquitin ligase complexes, which mediate much protein degradation, require CAND1 to distribute the limiting CUL1 subunit across the family of ∼70 diff...

Descripción completa

Detalles Bibliográficos
Autores principales: Baek, Kheewoong, Scott, Daniel C., Henneberg, Lukas T., King, Moeko T., Mann, Matthias, Schulman, Brenda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156175/
https://www.ncbi.nlm.nih.gov/pubmed/37028429
http://dx.doi.org/10.1016/j.cell.2023.02.035