Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex

Cortical circuits are composed predominantly of pyramidal-to-pyramidal neuron connections, yet their assembly during embryonic development is not well understood. We show that mouse embryonic Rbp4-Cre cortical neurons, transcriptomically closest to layer 5 pyramidal neurons, display two phases of ci...

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Detalles Bibliográficos
Autores principales: Munz, Martin, Bharioke, Arjun, Kosche, Georg, Moreno-Juan, Verónica, Brignall, Alexandra, Rodrigues, Tiago M., Graff-Meyer, Alexandra, Ulmer, Talia, Haeuselmann, Stephanie, Pavlinic, Dinko, Ledergerber, Nicole, Gross-Scherf, Brigitte, Rózsa, Balázs, Krol, Jacek, Picelli, Simone, Cowan, Cameron S., Roska, Botond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156177/
https://www.ncbi.nlm.nih.gov/pubmed/37071993
http://dx.doi.org/10.1016/j.cell.2023.03.025

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